※ Overview

PLMD (Protein Lysine Modifications Database) is an online data resource specifically designed for protein lysine modifications (PLMs). The PLMD 3.0 database was extended and adapted from our CPLA 1.0 (Compendium of Protein Lysine Acetylation) database (Liu et al., 2011) and CPLM 2.0 (Compendium of Protein Lysine Modifications) database (Liu et al., 2014), and the PLMD 3.0 release contains 284780 modification events in 53501 proteins for 20 types of PLMs, including Nε-lysine acetylation (Yang et al., 2007; Shahbazian et al., 2007; Smith et al., 2009), ubiquitination (Gao, et al., 2013), methylation (Chen, et al., 2006), sumoylation (Ren, et al., 2009; Xue, et al., 2006), glycation (Priego-Capote, et al., 2010), butyrylation (Chen, et al., 2007; Cheng, et al., 2009; Zhang, et al., 2009), crotonylation (Tan, et al., 2011), malonylation (Xie, et al., 2012), propionylation (Chen, et al., 2007; Cheng, et al., 2009; Zhang, et al., 2009), succinylation (Xie, et al., 2012; Zhang, et al., 2011), neddylation (Rabut, et al., 2014; Soucy, et al., 2010), glutarylation (Tan, et al., 2014; Hirschey, et al., 2015), hydroxylation (Uzawa, et al., 2003), biotinylation (Hassan, et al., 2008; Kuroishi, et al., 2011), 2-hydroxyisobutyrylation (Dai, et al., 2014), lipoylation (Posner, et al., 2013), formylation (Jiang, et al., 2007), carboxylation (Jimenez-Morales, et al., 2014), phosphoglycerylation (Moellering, R. E. and B. F. Cravatt, 2013) and prokaryotic pupylation (Liu, et al., 2011).

 

※ Substrate Search

       


                  

For publication of results please cite the following articles:


PLMD: an updated data resource of protein lysine modifications
Hangdong Xu, Jiaqi Zhou, Shaofeng Lin, Wankun Deng, Ying Zhang, Yu Xue.
Journal of Genetics and Genomics. 2017, 44 (5): 243–250.

[Abstract] [FREE Full Text] [Print PDF][Screen PDF][Supplemental Data]

CPLM: a database of protein lysine modifications
Zexian Liu, Yongbo Wang, Tianshun Gao, Zhicheng Pan, Han Cheng, Qing Yang,
Zhongyi Cheng, Anyuan Guo, Jian Ren, Yu Xue.
Nucleic Acids Research. 2014, 42: D531-D536.

[Abstract] [FREE Full Text] [Print PDF][Screen PDF][Supplemental Data]

CPLA 1.0: an integrated database of protein lysine acetylation
Zexian Liu, Jun Cao, Xinjiao Gao, Yanhong Zhou, Longping Wen, Xiangjiao Yang,
Xuebiao Yao, Jian Ren, Yu Xue.
Nucleic Acids Research. 2011, 39: D1029-D1034.

[Abstract] [FREE Full Text] [Print PDF][Screen PDF][Supplemental Data]